Summary:
SHLD2 Antibody Blocking Peptide
Cat：K111141P-Ag
| 【Derived From】： Synthetic |
| 【Amino Acid】： 270-320/835aa |
| 【Uniprot】： Q86V20 |
| 【Gene ID】： 54537 |
| 【Application】： Blocking Peptide of K111141P Antibody |
| 【Purification】： HPLC |
| 【Bioactive】： Not tested |
Store:
| 【Storage】： Store at -20℃，2 years.Avoid freeze/thaw cycles. |
| 【Formulation】： Lyophilized powder |
Background:
Component of the shieldin complex， which plays an important role in repair of DNA double-stranded breaks (DSBs) (PubMed:29656893， PubMed:29789392). During G1 and S phase of the cell cycle， the complex functions downstream of TP53BP1 to promote non-homologous end joining (NHEJ) and suppress DNA end resection (PubMed:29656893， PubMed:29789392). Mediates various NHEJ-dependent processes including immunoglobulin class-switch recombination， and fusion of unprotected telomeres (PubMed:29656893).
Verified picture
