Summary:
ENPP2 Antibody Blocking Peptide
Cat：K111498P-Ag
| 【Derived From】： Synthetic |
| 【Amino Acid】： 560-610/863aa |
| 【Uniprot】： Q13822 |
| 【Gene ID】： 5168 |
| 【Application】： Blocking Peptide of K111498P Antibody |
| 【Purification】： HPLC |
| 【Bioactive】： Not tested |
Store:
| 【Storage】： Store at -20℃，2 years.Avoid freeze/thaw cycles. |
| 【Formulation】： Lyophilized powder |
Background:
Hydrolyzes lysophospholipids to produce the signaling molecule lysophosphatidic acid (LPA) in extracellular fluids (PubMed:15769751， PubMed:26371182， PubMed:27754931， PubMed:14500380， PubMed:12354767，). Major substrate is lysophosphatidylcholine (PubMed:12176993， PubMed:27754931， PubMed:14500380). Also can act on sphingosylphosphorylcholine producing sphingosine-1-phosphate， a modulator of cell motility (PubMed:14500380). Can hydrolyze， in vitro， bis-pNPP， to some extent pNP-TMP， and barely ATP (PubMed:15769751， PubMed:12176993). Involved in several motility-related processes such as angiogenesis and neurite outgrowth. Acts as an angiogenic factor by stimulating migration of smooth muscle cells and microtubule formation (PubMed:11559573). Stimulates migration of melanoma cells， probably via a pertussis toxin-sensitive G protein (PubMed:1733949). May have a role in induction of parturition (PubMed:12176993). Possible involvement in cell proliferation and adipose tissue development (
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