Summary:
RAPGEF1 Antibody Blocking Peptide
Cat：K111587P-Ag
| 【Derived From】： Synthetic |
| 【Amino Acid】： 465-515/1077aa |
| 【Uniprot】： Q13905 |
| 【Gene ID】： 2889 |
| 【Application】： Blocking Peptide of K111587P Antibody |
| 【Purification】： HPLC |
| 【Bioactive】： Not tested |
Store:
| 【Storage】： Store at -20℃，2 years.Avoid freeze/thaw cycles. |
| 【Formulation】： Lyophilized powder |
Background:
Guanine nucleotide-releasing protein that binds to SH3 domain of CRK and GRB2/ASH. Transduces signals from CRK to activate RAS. Involved in cell branching and adhesion mediated by BCAR1-CRK-RAPGEF1 signaling and activation of RAP1. Plays a role in the establishment of basal endothelial barrier function. Plays a role in nerve growth factor (NGF)-induced sustained activation of Rap1 and neurite outgrowth.
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