Summary:
MAP4K4 Antibody Blocking Peptide
Cat：K112144P-Ag
| 【Derived From】： Synthetic |
| 【Amino Acid】： 560-610/1239aa |
| 【Uniprot】： O95819 |
| 【Gene ID】： 9448 |
| 【Application】： Blocking Peptide of K112144P Antibody |
| 【Purification】： HPLC |
| 【Bioactive】： Not tested |
Store:
| 【Storage】： Store at -20℃，2 years.Avoid freeze/thaw cycles. |
| 【Formulation】： Lyophilized powder |
Background:
The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase has been shown to specifically activate MAPK8/JNK. The activation of MAPK8 by this kinase is found to be inhibited by the dominant-negative mutants of MAP3K7/TAK1， MAP2K4/MKK4， and MAP2K7/MKK7， which suggests that this kinase may function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade， and mediate the TNF-alpha signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been identified.
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