Summary:
PARD3 Antibody Blocking Peptide
Cat：K112167P-Ag
| 【Derived From】： Synthetic |
| 【Amino Acid】： 630-680/1356aa |
| 【Uniprot】： Q8TEW0 |
| 【Gene ID】： 56288 |
| 【Application】： Blocking Peptide of K112167P Antibody |
| 【Purification】： HPLC |
| 【Bioactive】： Not tested |
Store:
| 【Storage】： Store at -20℃，2 years.Avoid freeze/thaw cycles. |
| 【Formulation】： Lyophilized powder |
Background:
Adapter protein involved in asymmetrical cell division and cell polarization processes (PubMed:27925688， PubMed:10954424). Seems to play a central role in the formation of epithelial tight junctions (PubMed:27925688). Targets the phosphatase PTEN to cell junctions (By similarity). Involved in Schwann cell peripheral myelination (By similarity). Association with PARD6B may prevent the interaction of PARD3 with F11R/JAM1， thereby preventing tight junction assembly (By similarity). The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins (PubMed:10934474). Required for establishment of neuronal polarity and normal axon formation in cultured hippocampal neurons (PubMed:19812038， PubMed:27925688).
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