COL4A5 Antibody Blocking Peptide

This gene encodes one of the six subunits of type IV collagen， the major structural component of basement membranes. Mutations in this gene are associated with X-linked Alport syndrome， also known as hereditary nephritis. Like the other members of the type IV collagen gene family， this gene is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter. Alternatively spliced transcript variants have been identified for this gene.