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DOCK1 Antibody Blocking Peptide

Cat:K112929P-Ag

Summary:

【Derived From】: Synthetic
【Amino Acid】: 1430-1480/1865aa
【Uniprot】: Q14185
【Gene ID】: 1793
【Application】: Blocking Peptide of K112929P Antibody
【Purification】: HPLC
【Bioactive】: Not tested

Store:

【Storage】: Store at -20℃,2 years.Avoid freeze/thaw cycles.
【Formulation】: Lyophilized powder

Background:

Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Along with DOCK1, mediates CRK/CRKL regulation of epithelial and endothelial cell spreading and migration on type IV collagen ;Functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. Its GEF activity may be enhanced by ELMO1

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