Summary:
RANGRF Antibody Blocking Peptide
Cat：K113151P-Ag
| 【Derived From】： Synthetic |
| 【Amino Acid】： 130-180/186aa |
| 【Uniprot】： Q9HD47 |
| 【Gene ID】： 29098 |
| 【Application】： Blocking Peptide of K113151P Antibody |
| 【Purification】： HPLC |
| 【Bioactive】： Not tested |
Store:
| 【Storage】： Store at -20℃，2 years.Avoid freeze/thaw cycles. |
| 【Formulation】： Lyophilized powder |
Background:
May regulate the intracellular trafficking of RAN (PubMed:11290418).Promotes guanine nucleotide release from RAN and inhibits binding of new GTP by preventing the binding of the RAN guanine nucleotide exchange factor RCC1 (PubMed:29040603).Regulates the levels of GTP-bound RAN in the nucleus， and thereby plays a role in the regulation of RAN-dependent mitotic spindle dynamics (PubMed:29040603).Enhances the expression of SCN5A at the cell membrane in cardiomyocytes (PubMed:18184654， PubMed:23420830， PubMed:21621375).
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