Summary:
TM4SF5 Antibody Blocking Peptide
Cat：K113156P-Ag
| 【Derived From】： Synthetic |
| 【Amino Acid】： 100-150/197aa |
| 【Uniprot】： O14894 |
| 【Gene ID】： 9032 |
| 【Application】： Blocking Peptide of K113156P Antibody |
| 【Purification】： HPLC |
| 【Bioactive】： Not tested |
Store:
| 【Storage】： Store at -20℃，2 years.Avoid freeze/thaw cycles. |
| 【Formulation】： Lyophilized powder |
Background:
Acts as a lysosomal membrane arginine sensor (PubMed:30956113).Forms a complex with MTOR and SLC38A9 on lysosomal membranes in an arginine-regulated manner， leading to arginine efflux which enables the activation of mTORC1 which subsequently leads to RPS6KB1 and EIF4EBP1 phosphorylations (PubMed:30956113).Facilitates cell cycle G1/S phase progression and the translocation of the CDK4-CCND1 complex into the nucleus (PubMed:20399237).CDKN1B and RHOA/ROCK signaling activity are involved in TM4SF5-mediated acceleration of G1/S phase progression (PubMed:20399237).
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