GPX3 Antibody Blocking Peptide

This gene product belongs to the glutathione peroxidase family， which functions in the detoxification of hydrogen peroxide. It contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon， which normally signals translation termination. The 3’ UTR of Sec-containing genes have a common stem-loop structure， the sec insertion sequence (SECIS)， which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal.