SF3B4 Antibody Blocking Peptide

This gene encodes one of four subunits of the splicing factor 3B. The protein encoded by this gene cross-links to a region in the pre-mRNA immediately upstream of the branchpoint sequence in pre-mRNA in the prespliceosomal complex A. It also may be involved in the assembly of the B， C and E spliceosomal complexes. In addition to RNA-binding activity， this protein interacts directly and highly specifically with subunit 2 of the splicing factor 3B. This protein contains two N-terminal RNA-recognition motifs (RRMs)， consistent with the observation that it binds directly to pre-mRNA. [provided by RefSeq， Jul 2008]