Summary:
BMP2 Antibody Blocking Peptide
Cat：K115140P-Ag
| 【Derived From】： Synthetic |
| 【Amino Acid】： 280-330/396aa |
| 【Uniprot】： P12643 |
| 【Gene ID】： 650 |
| 【Application】： Blocking Peptide of K115140P Antibody |
| 【Purification】： HPLC |
| 【Bioactive】： Not tested |
Store:
| 【Storage】： Store at -20°C. Avoid freeze / thaw cycles. |
| 【Formulation】： Lyophilized powder |
Background:
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer， which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of this gene causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients.
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