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Recombinant human HSP70 protein

Cat:P02346

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 443-600aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: HSP70
【Full Name】: heat shock 70kDa protein 1A
【Uniprot】: P0DMV8
【Gene ID】: 3303
【Species Reactivity】: Human Mouse Rat (Bovine Fruit fly Pig Dog Goat Pea)
【Mol Mass】: 18kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: No activity experimental data, to be verified.
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 10μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 2-7 days, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily.This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis.Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia.Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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