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Recombinant human NRF2/NFE2L2 protein

Cat:P02364

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 46-395aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: NRF2/NFE2L2
【Full Name】: Nuclear factor erythroid 2-related factor 2
【Uniprot】: Q16236
【Gene ID】: 4780
【Species Reactivity】: Human Mouse (Bovine)
【Mol Mass】: 38kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: N0
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins.The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters; many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals.Multiple transcript variants encoding different isoforms have been characterized for this gene

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