Summary:
Recombinant human TIMP1 protein
Cat：P02366
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 1-207aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： TIMP1 |
| 【Full Name】： TIMP metallopeptidase inhibitor 1 |
| 【Uniprot】： P01033 |
| 【Gene ID】： 7076 |
| 【Species Reactivity】： Human Mouse Rat (Bovine Pig Sheep Dog Rabbit Horse Macaque Gorilla) |
| 【Mol Mass】： 23kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
This gene belongs to the TIMP gene family.The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix.In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function.Transcription of this gene is highly inducible in response to many cytokines and hormones.In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females.This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction.
Verified picture
