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Recombinant human CDK2 protein

Cat:P02367

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 1-298aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: CDK2
【Full Name】: cyclin-dependent kinase 2
【Uniprot】: P24941
【Gene ID】: 1017
【Species Reactivity】: Human Mouse Rat (Bovine Fruit fly)
【Mol Mass】: 34kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: N0
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

This gene encodes a member of a family of serine/threonine protein kinases that participate in cell cycle regulation.The encoded protein is the catalytic subunit of the cyclin-dependent protein kinase complex, which regulates progression through the cell cycle.Activity of this protein is especially critical during the G1 to S phase transition.This protein associates with and regulated by other subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A), and p27Kip1 (CDKN1B).Alternative splicing results in multiple transcript variants.

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