Summary:
Recombinant human NUMA1 protein
Cat：P02376
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 845-1193aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： NUMA1 |
| 【Full Name】： nuclear mitotic apparatus protein 1 |
| 【Uniprot】： Q14980 |
| 【Gene ID】： 4926 |
| 【Species Reactivity】： Human Mouse |
| 【Mol Mass】： 38kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
This gene encodes a large protein that forms a structural component of the nuclear matrix.The encoded protein interacts with microtubules and plays a role in the formation and organization of the mitotic spindle during cell division.Chromosomal translocation of this gene with the RARA (retinoic acid receptor, alpha) gene on chromosome 17 have been detected in patients with acute promyelocytic leukemia.Alternative splicing results in multiple transcript variants.[provided by RefSeq, Nov 2013]
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