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Recombinant human LGALS3/Galectin-3 protein

Cat:P02377

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 1-250aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: LGALS3/Galectin-3
【Full Name】: Galectin-3
【Uniprot】: P17931
【Gene ID】: 3958
【Species Reactivity】: Human Mouse Rat (Bovine Zebrafish Dog Rabbit)
【Mol Mass】: 26kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: N0
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

This gene encodes a member of the galectin family of carbohydrate binding proteins.Members of this protein family have an affinity for beta-galactosides.The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain.This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands.This protein localizes to the extracellular matrix, the cytoplasm and the nucleus.This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation.The protein exhibits antimicrobial activity against bacteria and fungi.Alternate splicing results in multiple transcript variants.[provided by RefSeq, Oct 2014]

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