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Recombinant human BID protein

Cat:P02378

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 31-145aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: BID
【Full Name】: BH3 interacting domain death agonist
【Uniprot】: P55957
【Gene ID】: 637
【Species Reactivity】: Human Mouse Rat (Pig Chicken)
【Mol Mass】: 22kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: N0
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2.The encoded protein is a member of the BCL-2 family of cell death regulators.It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release.Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined.[provided by RefSeq, Jul 2008]

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