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Recombinant human BCL2 protein

Cat:P02388

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 1-168aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: BCL2
【Full Name】: B cell CLL/lymphoma 2
【Uniprot】: P10415
【Gene ID】: 596
【Species Reactivity】: Human Mouse Rat (Bovine Chicken Pig Dog)
【Mol Mass】: 26kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: N0
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes.Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma.Alternative splicing results in multiple transcript variants.

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