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Recombinant human SRC protein

Cat:P02390

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 98-537aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: SRC
【Full Name】: v-src sarcoma
【Uniprot】: P12931
【Gene ID】: 6714
【Species Reactivity】: Human Mouse Rat (Zebrafish Fruit fly Chicken Pig)
【Mol Mass】: 37kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: N0
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

This gene is highly similar to the v-src gene of Rous sarcoma virus.This proto-oncogene may play a role in the regulation of embryonic development and cell growth.The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase.Mutations in this gene could be involved in the malignant progression of colon cancer.Two transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Jul 2008].Expression.Ubiquitous expression in stomach (RPKM 19.0), testis (RPKM 19.0) and 25 other tissues

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