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Recombinant human SPP1 protein

Cat:P02393

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 75-280aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: SPP1
【Full Name】: secreted phosphoprotein 1
【Uniprot】: P10451
【Gene ID】: 6696
【Species Reactivity】: Human Mouse Rat (Bovine Pig Chicken Sheep Rabbit)
【Mol Mass】: 23kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: No activity experimental data, to be verified.
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 10μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 2-7 days, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

The protein encoded by this gene is involved in the attachment of osteoclasts to the mineralized bone matrix.The encoded protein is secreted and binds hydroxyapatite with high affinity.The osteoclast vitronectin receptor is found in the cell membrane and may be involved in the binding to this protein.This protein is also a cytokine that upregulates expression of interferon-gamma and interleukin-12.Several transcript variants encoding different isoforms have been found for this gene

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