Summary:
Recombinant human PPIA protein
Cat：P02394
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 1-165aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： PPIA |
| 【Full Name】： peptidylprolyl isomerase A |
| 【Uniprot】： P62937 |
| 【Gene ID】： 5478 |
| 【Species Reactivity】： Human Mouse Rat (Bovine Pig Rabbit Monkey Gorilla Macaque) |
| 【Mol Mass】： 18kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
This gene encodes a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family.PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins.The encoded protein is a cyclosporin binding-protein and may play a role in cyclosporin A-mediated immunosuppression.The protein can also interact with several HIV proteins, including p55 gag, Vpr, and capsid protein, and has been shown to be necessary for the formation of infectious HIV virions.Multiple pseudogenes that map to different chromosomes have been reported.
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