Summary:
Recombinant human myd88 protein
Cat：P02406
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 1-296aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： myd88 |
| 【Full Name】： myeloid differentiation primary response gene (88) |
| 【Uniprot】： Q99836 |
| 【Gene ID】： 4615 |
| 【Species Reactivity】： Human Mouse Rat (Bovine Zebrafish Chicken Pig Sheep Monkey Gorilla) |
| 【Mol Mass】： 33kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response.This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways.These pathways regulate that activation of numerous proinflammatory genes.The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain.Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections.Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010]
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