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Recombinant human BECN1 protein

Cat:P02418

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 141-450aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: BECN1
【Full Name】: beclin 1
【Uniprot】: Q14457
【Gene ID】: 8678
【Species Reactivity】: Human Mouse Rat (Bovine Zebrafish Pig Chicken Gorilla)
【Mol Mass】: 36kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: N0
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

This gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation.The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes.This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis.Alternative splicing results in multiple transcript variants.

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