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Recombinant human MEKK2 protein

Cat:P02420

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 30-330aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: MEKK2
【Full Name】: mitogen-activated protein kinase kinase kinase 2
【Uniprot】: Q9Y2U5
【Gene ID】: 10746
【Species Reactivity】: Human Mouse (A.thaliana)
【Mol Mass】: 33kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: N0
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

The protein encoded by this gene is a member of serine/threonine protein kinase family.This kinase preferentially activates other kinases involved in the MAP kinase signaling pathway.This kinase has been shown to directly phosphorylate and activate Ikappa B kinases, and thus plays a role in NF-kappa B signaling pathway.This kinase has also been found to bind and activate protein kinase C-related kinase 2, which suggests its involvement in a regulated signaling process.

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