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Recombinant human HTRA2 protein

Cat:P02421

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 91-358aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: HTRA2
【Full Name】: HtrA serine peptidase 2
【Uniprot】: O43464
【Gene ID】: 27429
【Species Reactivity】: Human Mouse (Bovine Fruit fly)
【Mol Mass】: 28kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: N0
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

This gene encodes a serine protease.The protein has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen-activated protein kinase 14.The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus.The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat-containing 4.Nuclear localization of this protein has also been observed.Alternate splicing of this gene results in multiple transcript variants encoding different isoforms.

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