Summary:
Recombinant human ITGA5 protein
Cat：P02422
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 749-1049aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： ITGA5 |
| 【Full Name】： integrin，alpha 5 |
| 【Uniprot】： P08648 |
| 【Gene ID】： 3678 |
| 【Species Reactivity】： Human Mouse (Bovine) |
| 【Mol Mass】： 34kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
The product of this gene belongs to the integrin alpha chain family.Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling.The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit.This subunit associates with the beta 1 subunit to form a fibronectin receptor.This integrin may promote tumor invasion, and higher expression of this gene may be correlated with shorter survival time in lung cancer patients.Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.
Verified picture
