Summary:
Recombinant human RPSA protein
Cat：P02498
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 1-295aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： RPSA |
| 【Full Name】： ribosomal protein SA |
| 【Uniprot】： P08865 |
| 【Gene ID】： 3921 |
| 【Species Reactivity】： Human Mouse Rat (Bovine Zebrafish Pig Sheep) |
| 【Mol Mass】： 33kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes.They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis.Many of the effects of laminin are mediated through interactions with cell surface receptors.These receptors include members of the integrin family, as well as non-integrin laminin-binding proteins.This gene encodes a high-affinity, non-integrin family, laminin receptor 1.This receptor has been variously called 67 kD laminin receptor, 37 kD laminin receptor precursor (37LRP) and p40 ribosome-associated protein.The amino acid sequence of laminin receptor 1 is highly conserved through evolution, suggesting a key biological function.It has been observed that the level of the laminin receptor transcript is higher in colon carcinoma tissue and lung cancer cell line than their normal counterparts.Also, there is a correlation between t
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