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Recombinant human PUS7 protein

Cat:P02522

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 403-660aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: PUS7
【Full Name】: pseudouridylate synthase 7 homolog (S. cerevisiae)
【Uniprot】: Q96PZ0
【Gene ID】: 54517
【Species Reactivity】: Human Mouse (Bovine Zebrafish)
【Mol Mass】: 30kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: N0
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

Staufen homolog 2 is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles.These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures.Staufen homolog 2 shares 48.5% and 59.9% similarity with drosophila and human staufen, respectively.The exact function of Staufen homolog 2 is not known, but since it contains 3 copies of conserved dsRNA binding domain, it could be involved in double-stranded RNA binding events.Several transcript variants encoding different isoforms have been found for this gene.

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