Summary:
Recombinant human TTC26 protein
Cat：P03196
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 1-272aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： TTC26 |
| 【Full Name】： tetratricopeptide repeat domain 26 |
| 【Uniprot】： A0AVF1 |
| 【Gene ID】： 79989 |
| 【Species Reactivity】： Human Mouse Rat (Zebrafish) |
| 【Mol Mass】： 30kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
Component of the intraflagellar transport (IFT) complex B required for transport of proteins in the motile cilium.Required for transport of specific ciliary cargo proteins related to motility, while it is neither required for IFT complex B assembly or motion nor for cilium assembly.Required for efficient coupling between the accumulation of GLI2 and GLI3 at the ciliary tips and their dissociation from the negative regulator SUFU.Plays a key role in maintaining the integrity of the IFT complex B and the proper ciliary localization of the IFT complex B components.Not required for IFT complex A ciliary localization or function.Essential for maintaining proper microtubule organization within the ciliary axoneme.
Verified picture
