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Recombinant human FTH1 protein

Cat:P03506

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 1-183aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: FTH1
【Full Name】: ferritin,heavy polypeptide 1
【Uniprot】: P02794
【Gene ID】: 2495
【Species Reactivity】: Human (Bovine Mouse Rat Pig Dog Sheep Horse Gorilla)
【Mol Mass】: 21kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: N0
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

This gene encodes the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes.It is composed of 24 subunits of the heavy and light ferritin chains.Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues.A major function of ferritin is the storage of iron in a soluble and nontoxic state.Defects in ferritin proteins are associated with several neurodegenerative diseases.This gene has multiple pseudogenes.Several alternatively spliced transcript variants have been observed, but their biological validity has not been determined.

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