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Recombinant human FNTA protein

Cat:P03508

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 1-379aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: FNTA
【Full Name】: farnesyltransferase,CAAX box,alpha
【Uniprot】: P49354
【Gene ID】: 2339
【Species Reactivity】: Human Mouse Rat (Bovine)
【Mol Mass】: 44kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: N0
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

Prenyltransferases can attach either a farnesyl group or a geranylgeranyl group in thioether linkage to the cysteine residue of proteins with a C-terminal CAAX box.CAAX geranylgeranyltransferase and CAAX farnesyltransferase are heterodimers that share the same alpha subunit but have different beta subunits.This gene encodes the alpha subunit of these transferases.Alternative splicing results in multiple transcript variants.Related pseudogenes have been identified on chromosomes 11 and 13.

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