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Product Introduction:
The purpose of fix is to preserve the original morphological structure of cells and tissues. The fixative can prevent the autolysis of endogenous lysosomal enzymes to their own tissues and cells and inhibit the growth of bacteria and molds. The fixative makes the internal structure of the protein change by coagulating and adding compounds, which is to make the enzyme inactivated. The fixative can be divided into aldehyde fixative, mercury fixative, alcohol fixative, oxidant fixative, picric acid salt fixative, etc. Formaldehyde in aldehydes and alcohol in alcohols are more commonly used.
Carnoy's Fluid, also known as Carnoy's Fixative, is a mixture of ethanol and acetic acid. It is often used for animal and plant compression and paraffin sections, etc. It has extremely fast penetration and can be fixed for no more than 24 h at most. It can penetrate cells rapidly, fix them and maintain the integrity of chromosome structure. It can also enhance the basophil of chromosome and achieve excellent staining effect. It can be used for the tissue fixation of RNA and DNA staining, and also for the tissue fixation of glycogen staining, which can make glycogen present fine granules. Because of its strong penetration, it can also fix the outer membrane of the tissue which is dense and impervious. The tissue can be stored in 70% ethanol after tissue fixation.
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