Leupeptin
Cat.No：L8110 Solarbio
CAS：103476-89-7
Molecular Formula：C20H38N6O4·1/2(H2SO4)
Molecular Weight：475.59
Appearance：White powder
Storage：Store at -20℃，2 years
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Colloidal Gold Reagent
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Purified Secondary Antibodies
Allophycocyanin(APC)-Conjugated
CY Fluorescent-Conjugated
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Inhibitors & Antagonists & Agonists
PI3K/Akt/mTOR
Endocrinology & Hormones
Protein Tyrosine Kinase/PTK
Angiogenesis
HIF
Immunology & Inflammation
Stem Cells
Apoptosis
Metabolic Enzyme & Protease
Autophagy
ER Stress
Cell Cycle
Cytoskeleton
DNA Damage & DNA Repai
Epigenetics
Ubiquitin
JAK/STAT
GPCR & G Protein
Neuronal Signal Pathway
MAPK
NF-κB
Membrane Transporter & Ion Channel
TGF-β/Smad
Hippo
Antibody-drug Conjugate/ADC Related
Others
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Instruments
Pipette & Dispenser & Pipette Dispensing Instrument
Oscillating Mixing & Stirring & Dispersing Instrument
Temperature Control & Sampling & Grinding Crushing Instrument
Sterilization & Filtration Instruments
PCR Instrument & Light Glue Instrument
Spectrophotometer
Centrifuge
Shaker
Vacuum Pump
Other Small Instruments
Product Information
| Name | Leupeptin |
| CAS | 103476-89-7 |
| Molecular Formula | C20H38N6O4·1/2(H2SO4) |
| Molecular Weight | 475.59 |
| Storage | Store at -20℃，2 years |
| Appearance | White powder |
| Unit | Piece |
| Specification | 2mg 5mg |
Product introduction
A trypsin inhibitor produced by Streptomyces roseus MB-26-AI, which is one of many protease inhibitors. Leupeptin can inhibit trypsin, papain, cathepsin B, plasmin, kallikrein, etc., and its inhibitory effect is competitive with the substrate. The IC50(half-inhibitory concentration) of plasmin was 8μg/ml, but it did not inhibit chymotrypsin.
Scope of application
1) As a protease inhibitor, it can be directly soluble in water with a solubility of 50mg/ml;
2) The 10mM aqueous solution was stable at 4℃ for 1 week and -20℃ for 6 months;
3) The working concentration is generally 10-100mM and is used on ice.
Note：Product information may be optimized and upgraded. Please refer to the actual label information for accuracy.
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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Related Paper
Enantioselective Degrader for Elimination of Extracellular Aggregation-Prone Proteins hIAPP Associated with Type 2 Diabetes
Click to check >>Author：Zhenqi Liu, Dongqin Yu, Hualong Song, Miles L. Postings, Peter Scott, Zhao Wang, Jinsong Ren, Xiaogang Qu
IF：18.0270
Publish_to：ACS Nano
PMID：37057955
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