Use and synthesis method:

Used in scientific research reagents, widely used in molecular biology, pharmacology and other scientific research.

This product is an antiepileptic and antiarrhythmic drug. Therapeutic dose does not induce sedation and hypnosis,

Animal experiments have proved that this product has a selective antagonistic effect on the tetanic phase of super electric shock and convulsion, and is ineffective or aggravated against the clonic phase, so it has a good effect on the grand seizure, but is ineffective on the absence of seizures. The mechanism of its anti-epileptic action has not been clarified. It is generally believed that it can stabilize the nerve membrane by increasing the sodium ion membrane outflow or reducing the sodium ion internal flow, raise the excitation threshold, and reduce the spread of high-frequency discharge in the lesion.

In addition, this product can shorten the action potential interval and effective refractory period, inhibit calcium ion flow, reduce myocardial automaticity, inhibit the sympathetic center, inhibit the ectopic rhythm point of atrium and ventricle, and increase the threshold value of atrial fibrillation and ventricular fibrillation.

It stabilizes cell membrane and reduces synaptic transmission, and has antineuralgic and skeletal muscle relaxation effects.

This product can inhibit the synthesis (or) secretion of collagenase by skin fibroblasts. It can also accelerate vitamin D metabolism, can cause lymph node enlargement, has an anti-folic acid effect, has an inhibitory effect on the hematopoietic system, can cause allergic reactions, has an enzyme induction effect, and intravenous medication can expand peripheral blood vessels.

Solubility:

Soluble in water, soluble in ethanol, almost insoluble in trichloromethane or ether

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