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Chemical Synthesis
Your Position: Home > Biochemical Reagents > Antibiotics (Biochemical Reagents) > Amphotericin B
Amphotericin B

CAS:1397-89-3

Appearance:Yellow to orange powder

Storage:2-8℃, avoid light and moisture and store with seal.

  A8251Manual
Amphotericin B
Cat.No：
A8251
Brand：
Solarbio
SKU Tongzhou Beijing Haidian Beijing Wuhan Guangzhou
A8251-100mg Inquiry Inquiry Inquiry Inquiry
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Product Information Related Products Related Paper COA Technical Q&A

Description:

IC50:

Trichophyton palpis: IC50 = 0.02μg /ml;

Leishmania dunalii: IC50 = 0.06μg /ml;

Candida albicans: EC50= 0.25μg /ml;

half

Lethal dose (LD50) orally (rats)>5,000 mg/kg

Use and synthesis method:

Amphotericin is a polyene antibiotic produced by Streptomyces nodosus M4575. Amphotericin contains two components, A component is less toxic, weak anti-fungal action, not used in clinical use, B component is strong, called amphotericin B. Amphotericin B is a polyene antifungal antibiotic that inhibits fungal growth by affecting cell membrane permeability. It is clinically used to treat severe visceral or systemic infections caused by deep fungi. The product has a strong inhibition or killing effect on a variety of fungal infections, such as cryptococcus neoformans, Candida albicans, histoplasma capsulatus, odontococcus dermatitis, Sporotrichia Schenckii, mucor and coccidioides. It is mainly used as the first choice for deep fungal diseases.

Physical shape:

Density: 1.34g /cm3(forecast)

Solubility:

Soluble in dmso, slightly soluble in dimethylformamide, very slightly soluble in methanol; Insoluble in water, anhydrous ethanol, trichloromethane or ether.

Note: Our products are non-aseptic packaging, if used for cell culture, please do pre-treatment in advance to remove pyrogen bacteria, otherwise it will lead to contamination. The above data is for communication purposes only.

Note：Product information may be optimized and upgraded. Please refer to the actual label information for accuracy.

Remark：
These protocols are for reference only. Solarbio does not independently validate these methods.

Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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