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CAS:1397-89-3
Appearance:Yellow to orange powder
Storage:Store at 2-8℃，avoid light and moisture，keep seal，3 years
Description:
IC50:
Trichophyton palpis: IC50 = 0.02μg /ml;
Leishmania dunalii: IC50 = 0.06μg /ml;
Candida albicans: EC50= 0.25μg /ml;
halfLethal dose (LD50) orally (rats)>5,000 mg/kg
Use and synthesis method:
Amphotericin is a polyene antibiotic produced by Streptomyces nodosus M4575. Amphotericin contains two components, A component is less toxic, weak anti-fungal action, not used in clinical use, B component is strong, called amphotericin B. Amphotericin B is a polyene antifungal antibiotic that inhibits fungal growth by affecting cell membrane permeability. It is clinically used to treat severe visceral or systemic infections caused by deep fungi. The product has a strong inhibition or killing effect on a variety of fungal infections, such as cryptococcus neoformans, Candida albicans, histoplasma capsulatus, odontococcus dermatitis, Sporotrichia Schenckii, mucor and coccidioides. It is mainly used as the first choice for deep fungal diseases.
Physical shape:
Density: 1.34g /cm3(forecast)
Solubility:
Soluble in dmso, slightly soluble in dimethylformamide, very slightly soluble in methanol; Insoluble in water, anhydrous ethanol, trichloromethane or ether.
Note: Our products are non-aseptic packaging, if used for cell culture, please do pre-treatment in advance to remove pyrogen bacteria, otherwise it will lead to contamination. The above data is for communication purposes only.
Note：Product information may be optimized and upgraded. Please refer to the actual label information for accuracy.
这个需要配到什么浓度才可以用呢，两性霉素B2022-07-04 14:38:17
Administrator不同筛选实验工作浓度不同，可参考相关文献或设置不同浓度梯度进行预实验