Products
Plasmocin™ Treatment
Plasmocin™ Treatment
Cat.No:
ant-mpt
Brand:
InvivoGen

Plasmocin? - Mycoplasma Elimination ReagentElimination and Prevention of Mycoplasma Contamination in Cell CulturesPlasmocin? is used to cure cell lines infected by mycoplasma and related cell wall-less bacteria.
Plasmocin? can also be used as a routine addition in liquid media to prevent mycoplasma and more generally bacterial contamination in small and large animal cell cultures.
More info on Mycoplasma eradication
Plasmocin? is a well-established antimycoplasma reagent. It contains two bactericidal components strongly active against mycoplasmas that allow their elimination in only 2 weeks.
The first component acts on the protein synthesis machinery while the second acts on the DNA replication. These two specific and separate targets are found only in mycoplasmas and many other bacteria and are completely absent in eukaryotic cells.
Plasmocin? is also active at low concentrations on a broad range of Gram positive and Gram negative bacteria that are otherwise resistant to the mixture of streptomycin and penicillin, and exhibits no toxicity in eukaryotic cells.
Many cell lines infected by mycoplasmas have been successfully treated with Plasmocin? [1], including primary cancer cell lines [2], virus producing cells [3] and induced pluripotent stem cells [4], without inducing any permanent alterations. Further, in a recent study, a 2 week treatment with Plasmocin was found to effectively cure mycoplasma contamination in human embryonic stem cells without affecting their stemness and pluripotency nor cell viability [5]

Remark:
These protocols are for reference only. Solarbio does not independently validate these methods.

Note:
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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