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My CartCAS：59865-13-3
Purity：HPLC≥98%
Molecular Formula：C62H111N11O12
Molecular Weight：1202.61
Appearance：White to off-white powder
Storage：Store at 2-8℃，2 years.
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| CAS | 59865-13-3 |
| Name | Cyclosporine A |
| Purity | HPLC≥98% |
| Molecular Formula | C62H111N11O12 |
| Molecular Weight | 1202.61 |
| Appearance | White to off-white powder |
| Solubility | ≥10mg/mL in Ethanol/DMSO |
| Storage | Store at 2-8℃，2 years. |
| EC | EINECS 200-835-2 |
| MDL | MFCD00274558 |
| SMILES | O[C@@H]([C@](C(N[C@H](C(N(CC(N([C@H](C(N[C@@](C(N([C@H]1CC(C)C)C)=O)([H])C(C)C)=O)CC(C)C)C)=O)C)=O)CC)=O)([H])N(C([C@](N(C([C@@H](N(C([C@H](N(C([C@H](NC([C@@H](NC1=O)C)=O)C)=O)C)CC(C)C)=O)C)CC(C)C)=O)C)([H])C(C)C)=O)C)[C@H](C)C/C=C/C |
| InChI | InChI=1S/C62H111N11O12/c1-25-27-28-40(15)52(75)51-56(79)65-43(26-2)58(81)67(18)33-48(74)68(19)44(29-34(3)4)55(78)66-49(38(11)12)61(84)69(20)45(30-35(5)6)54(77)63-41(16)53(76)64-42(17)57(80)70(21)46(31-36(7)8)59(82)71(22)47(32-37(9)10)60(83)72(23)50(39(13)14)62(85)73(51)24/h25，27，34-47，49-52，75H，26，28-33H2，1-24H3，(H，63，77)(H，64，76)(H，65，79)(H，66，78)/b27-25+/t40-，41+，42-，43+，44+，45+，46+，47+，49+，50+，51+，52-/m1/s1 |
| Note | The reserve liquid is recommended to be packaged and frozen to avoid repeated freezing and thawing (-20℃, 1 month); The diluted working liquid is recommended to be used and prepared immediately |
| Unit | Bottle |
| Specification | 20mg |
来源：合成
复检期2年。
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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TRPV4-mediated mitochondrial dysfunction induces pyroptosis and cartilage degradation in osteoarthritis via the Drp1-HK2 axis
Click to check >>Author：Zijian Yan, Zili He, Hongyi Jiang, Yu Zhang, Yitie Xu, Yingze Zhang
IF：5.6000
Publish_to：INTERNATIONAL IMMUNOPHARMACOLOGY
PMID：37506502
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