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CAS:1950-01-01
Appearance:White crystalline powder
Storage:Store at RT，2 years
Purity:≥98.0%
Product introduction
(1) As a protein denaturant, it can dissolve some insoluble or denatured proteins, such as endosomes; It can also be used for the initial folding of active proteins or enzymes.
(2) was used as a strong denaturant in the experiment of extracting total RNA from cells. Guanidine hydrochloride solution can dissolve proteins, resulting in structural destruction of the cell, destruction of the secondary structure of the nuclear protein, and dissociation from the nucleic acid. It is also able to sufficiently inhibit ribonuclease activity in cells and whole tissues. Because of its biological destructive properties, buffers containing guanidine hydrochloride or guanidine thiocyanate are often called dissociative buffers.
Precautions
Guanidine hydrochloride Storage conditions: dry and cool at room temperature;
Guanidine hydrochloride Acute toxicity: toxic, intraperitoneal median lethal dose 500mg/kg in mice. It's irritating.
Guanidine hydrochloride Precautions: Guanidine hydrochloride is toxic, personal protection should be carefully done when using it.
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