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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Apoptosis > Ardisiacripsin BCAS：112766-96-8
Molecular Formula：C53H86O22
Molecular Weight：1075.24
Storage：Powder:2-8℃，2 years
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 112766-96-8 |
| Name | Ardisiacripsin B |
| Molecular Formula | C53H86O22 |
| Molecular Weight | 1075.24 |
| Solubility | Soluble in --- |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years |
| SMILES | C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)O[C@@H]2[C@H]([C@@H]([C@H](O[C@H]2O[C@H]3CO[C@H]([C@@H]([C@H]3O)O[C@H]4[C@@H]([C@H]([C@@H](C(O4)CO)O)O)O)O[C@H]5CC[C@@]6([C@H]7CCC89[C@@H]1C[C@@](CCC1(CO8)[C@@H](C[C@]9([C@@]7(CC[C@H]6C5(C)C)C)C)O)(C)C=O)C)CO)O)O)O)O)O |
| InChIKey | ZDIHSHLFPFGAGP-GRWMUYEGSA-N |
| InChI | InChI=1S/C53H86O22/c1-23-32(58)36(62)39(65)43(69-23)75-42-38(64)34(60)25(19-55)71-46(42)72-26-20-67-45(41(35(26)61)74-44-40(66)37(63)33(59)24(18-54)70-44)73-31-10-11-49(5)27(47(31，2)3)8-12-50(6)28(49)9-13-53-29-16-48(4，21-56)14-15-52(29，22-68-53)30(57)17-51(50，53)7/h21，23-46，54-55，57-66H，8-20，22H2，1-7H3/t23-，24?，25+，26-，27-，28+，29+，30+，31-，32-，33+，34+，35-，36+，37-，38-，39+，40+，41+，42+，43-，44-，45-，46-，48-，49-，50+，51-，52?，53?/m0/s1 |
| PubChem CID | 194981 |
| Target Point | Apoptosis; Ferroptosis |
| Passage | Apoptosis |
| Background | It was reported that Ardisiacrispin B induced apoptosis of CCRF-CEM cells by activating promoter caspase 8, 9 and effector caspase 3/7, altering MMP and increasing ROS production. |
| Biological Activity | A naturally occuring triterpene saponin ardisiacrispin B displayed cytotoxic effects in multi-factorial drug resistant cancer cells via ferroptotic and apoptotic cell death[1] |
| Data Literature Source | [1]. Armelle T Mbaveng，et al. A naturally occuring triterpene saponin ardisiacrispin B displayed cytotoxic effects in multi-factorial drug resistant cancer cells via ferroptotic and apoptotic cell death. Phytomedicine. 2018 Apr 1;43:78-85. |
| Unit | Bottle |
| Specification | 5mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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