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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Autophagy > EN6CAS：1808714-73-9
Molecular Formula：C19H14F2N4O2
Molecular Weight：368.34
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 1808714-73-9 |
| Name | EN6 |
| Molecular Formula | C19H14F2N4O2 |
| Molecular Weight | 368.34 |
| Solubility | Soluble in DMSO(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD31665468 |
| SMILES | C=CC(=O)NC1=C(C=CC(=C1)NC(=O)C2=CN(N=C2)C3=CC=CC=C3F)F |
| InChIKey | SUSXQEYPNDORDQ-UHFFFAOYSA-N |
| InChI | InChI=1S/C19H14F2N4O2/c1-2-18(26)24-16-9-13(7-8-14(16)20)23-19(27)12-10-22-25(11-12)17-6-4-3-5-15(17)21/h2-11H，1H2，(H，23，27)(H，24，26) |
| PubChem CID | 99640033 |
| Target Point | Autophagy |
| Passage | Autophagy |
| Background | It is a small molecule in vivo autophagy activator that covalently targets cysteine 277 in the ATP6V1A subunit of lysosomal V-ATPase. En6-mediated ATP6V1A modification uncoupled V-ATPase from Rag, resulting in inhibition of mTORC1 signaling, increased lysosomal acidification, and activation of autophagy. |
| Unit | Bottle |
| Specification | 1mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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