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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Others > DropropizineCAS：17692-31-8
Molecular Formula：C13H20N2O2
Molecular Weight：236.31
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 17692-31-8 |
| Name | Dropropizine |
| Molecular Formula | C13H20N2O2 |
| Molecular Weight | 236.31 |
| Solubility | Soluble in DMSO ≥3mg/mL |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 241-683-7 |
| MDL | MFCD00079124 |
| SMILES | C1CN(CCN1CC(CO)O)C2=CC=CC=C2 |
| InChIKey | PTVWPYVOOKLBCG-UHFFFAOYSA-N |
| InChI | InChI=1S/C13H20N2O2/c16-11-13(17)10-14-6-8-15(9-7-14)12-4-2-1-3-5-12/h1-5，13，16-17H，6-11H2 |
| PubChem CID | 3169 |
| Target Point | Others |
| Passage | Others |
| Background | Dropropizine has antitussive activity, which inhibits cough reflex by acting on peripheral receptors and its afferent conductors, and is often used in studies related to antitussive drugs. |
| Biological Activity | Dropropizine是一种外消旋的非鸦片类镇咳剂，用来作为止咳药。[1-2] |
| Data Literature Source | [1]. Slamenová D，et al. Results of genotoxicity testing of mazindol (degonan)，lithium carbonicum (contemnol) and dropropizine (ditustat) in Chinese hamster V79 and human EUE cells. Mutat Res. 1986 Mar;169(3): 171-7. [2]. Sutovska M，Franova S，Sutovsky J. The influence of animal species on the relationship between ATP-sensitive potassium ion channels and defense reflexes of the airways. Bratisl Lek Listy. 2009;110(5): 269-75. [3]. Nosá ová G，Mokry J，Ather A，et al. Antitussive activity of the ethanolic extract of Paederia foetida (Rubiaceae family) in non-anaesthetized cats[J]. Acta Veterinaria Brno，2007，76(1): 27-33. [4]. Nosál'ová G，Kardosová A，Franová S. Antitussive activity of a glucuronoxylan from Rudbeckia fulgida compared to the potency of two polysaccharide complexes from the same herb. Pharmazie. 2000 Jan;55(1): 65-8. |
| Unit | Bottle |
| Specification | 200mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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