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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Metabolic Enzyme & Protease > EliglustatCAS：491833-29-5
Molecular Formula：C23H36N2O4
Molecular Weight：404.54
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 491833-29-5 |
| Name | Eliglustat |
| Molecular Formula | C23H36N2O4 |
| Molecular Weight | 404.54 |
| Solubility | Soluble in DMSO ≥5mg/mL |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD19443735 |
| SMILES | CCCCCCCC(=O)NC(CN1CCCC1)C(C2=CC3=C(C=C2)OCCO3)O |
| InChIKey | FJZZPCZKBUKGGU-AUSIDOKSSA-N |
| InChI | InChI=1S/C23H36N2O4/c1-2-3-4-5-6-9-22(26)24-19(17-25-12-7-8-13-25)23(27)18-10-11-20-21(16-18)29-15-14-28-20/h10-11，16，19，23，27H，2-9，12-15，17H2，1H3，(H，24，26)/t19-，23-/m1/s1 |
| PubChem CID | 23652731 |
| Target Point | glucocerebroside synthase |
| Passage | Metabolic Enzyme&Protease |
| Background | It is a highly effective and specific glucocerebroside synthase inhibitor. |
| Biological Activity | Eliglustat 是葡萄糖神经酰胺合成酶（GCS）的抑制剂，在MDCK细胞中IC50为20 nM。[1] |
| IC50 | glucocerebroside synthase: 20nM(IC50)[1] |
| Data Literature Source | [1]. Shayman JA. ELIGLUSTAT TARTRATE: Glucosylceramide Synthase Inhibitor Treatment of Type 1 Gaucher Disease. Drugs Future. 2010 Aug 1;35(8): 613-620. [2]. Yew NS，et al. Increased hepatic insulin action in diet-induced obese mice following inhibition of glucosylceramide synthase. PLoS One. 2010 Jun 21;5(6): e11239. |
| Unit | Bottle |
| Specification | 5mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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