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My CartCAS：61438-64-0
Molecular Formula：C22H13Cl2I2N2NaO2
Molecular Weight：685.06
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：Light yellow to yellow Solid
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| CAS | 61438-64-0 |
| Name | Closantel Sodium |
| Molecular Formula | C22H13Cl2I2N2NaO2 |
| Molecular Weight | 685.06 |
| Solubility | Soluble in DMSO ≥5mg/mL |
| Purity | ≥98% |
| Appearance | Light yellow to yellow Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 262-794-7 |
| MDL | MFCD03427328 |
| SMILES | CC1=CC(=C(C=C1NC(=O)C2=C(C(=CC(=C2)I)I)[O-])Cl)C(C#N)C3=CC=C(C=C3)Cl.[Na+] |
| InChIKey | LREGMDNUOGTSIK-UHFFFAOYSA-M |
| InChI | InChI=1S/C22H14Cl2I2N2O2.Na/c1-11-6-15(17(10-27)12-2-4-13(23)5-3-12)18(24)9-20(11)28-22(30)16-7-14(25)8-19(26)21(16)29;/h2-9，17，29H，1H3，(H，28，30);/q;+1/p-1 |
| PubChem CID | 23683671 |
| Target Point | Parasite |
| Passage | Anti-infection |
| Background | Closantel is a compound with potent antiparasitic activity. Closantel is a potent and highly specific inhibitor of onchocernia chitinase (OvCHT1). |
| Biological Activity | Closantel Sodium 是一种具有有效抗寄生虫活性的卤化水杨酸苯胺。是一种高效、高特异性的Onchocerca volvulus chitinase (OvCHT1)抑制剂，IC50为1.6 μM，Ki为468 nM。[1] |
| Data Literature Source | [1]. Garner AL，et al. Design，synthesis，and biological activities of closantel analogues: structural promiscuity and its impact on Onchocerca volvulus. J Med Chem. 2011 Jun 9;54(11): 3963-72. |
| Unit | Bottle |
| Specification | 100mg 250mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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