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My CartCAS：69655-05-6
Molecular Formula：C10H12N4O3
Molecular Weight：236.23
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 69655-05-6 |
| Name | Didanosine |
| Molecular Formula | C10H12N4O3 |
| Molecular Weight | 236.23 |
| Solubility | Soluble in DMSO ≥5mg/mL |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 614-994-4 |
| MDL | MFCD00077728 |
| SMILES | C1CC(OC1CO)N2C=NC3=C2N=CNC3=O |
| InChIKey | BXZVVICBKDXVGW-NKWVEPMBSA-N |
| InChI | InChI=1S/C10H12N4O3/c15-3-6-1-2-7(17-6)14-5-13-8-9(14)11-4-12-10(8)16/h4-7，15H，1-3H2，(H，11，12，16)/t6-，7+/m0/s1 |
| PubChem CID | 135398739 |
| Target Point | Reverse Transcriptase;HIV |
| Passage | Anti-infection |
| Background | It is an effective inhibitor of nucleoside reverse transcriptase, which has anti-HIV activity. |
| Biological Activity | Didanosine 是一种强效口服活性双脱氧核苷类似物，也是一种强效核苷类逆转录酶抑制剂。对艾滋病毒具有抗逆转录病毒活性。[1-3] |
| Data Literature Source | [1]. Nassar，et al.[Analytical Profiles of Drug Substances and Excipients] Volume 22 || Didanosine[J]. 1993:185-227.DOI:10.1016/S0099-5428(08)60242-7. [2]. Braga Neto MB，et al. Evaluation of HIV protease and nucleoside reverse transcriptase inhibitors on proliferation，necrosis，apoptosis in intestinal epithelial cells and electrolyte and water transport and epithelial barrier function in mice. BMC Gastroenterol. 2010 Aug 11;10:90. [3]. Perry，et al. Didanosine. Drugs 58，1099–1135 (1999). https://doi.org/10.2165/00003495-199958060-00009 |
| Unit | Bottle |
| Specification | 5mg 10mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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