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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > GPCR & G Protein > EbastineCAS：90729-43-4
Molecular Formula：C32H39NO2
Molecular Weight：469.66
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 90729-43-4 |
| Name | Ebastine |
| Molecular Formula | C32H39NO2 |
| Molecular Weight | 469.66 |
| Solubility | Soluble in Ethanol ≥5mg/mL;Soluble in Water/DMSO ≥0.5mg/mL |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD00865661 |
| SMILES | CC(C)(C)C1=CC=C(C=C1)C(=O)CCCN2CCC(CC2)OC(C3=CC=CC=C3)C4=CC=CC=C4 |
| InChIKey | MJJALKDDGIKVBE-UHFFFAOYSA-N |
| InChI | InChI=1S/C32H39NO2/c1-32(2，3)28-18-16-25(17-19-28)30(34)15-10-22-33-23-20-29(21-24-33)35-31(26-11-6-4-7-12-26)27-13-8-5-9-14-27/h4-9，11-14，16-19，29，31H，10，15，20-24H2，1-3H3 |
| PubChem CID | 3191 |
| Target Point | Histamine H1 Receptor |
| Passage | GPCR & G Protein;Neuronal Signaling;Immunology & Inflammation |
| Background | It is a second generation histamine H1 receptor antagonist, which can be used for the study of allergic rhinitis symptoms and chronic idiopathic urticaria. |
| Biological Activity | Ebastine 是一种口服活性的第二代组胺H1受体拮抗剂，可用于变应性鼻炎和慢性特发性荨麻疹的症状研究。[1] |
| Data Literature Source | [1]. Sastre J. Ebastine in allergic rhinitis and chronic idiopathic urticaria. Allergy. 2008 Dec;63 Suppl 89:1-20. [2]. Tsai FM，et al. Extracellular Signal-Regulated Kinase Mediates Ebastine-Induced Human Follicle Dermal Papilla Cell Proliferation. Biomed Res Int. 2019 Feb 11;2019:6360503. [3]. Fujii T，et al. Absorption，distribution，metabolism and excretion of [14C]ebastine after a single administration in rats. Arzneimittelforschung. 1994 Apr;44(4):527-38. |
| Unit | Bottle |
| Specification | 500mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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