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My Cart> Small Molecule Compounds > Anti-Infection > Anti-Fungal > Fenticonazole NitrateCAS：73151-29-8
Molecular Formula：C24H21Cl2N3O4S
Molecular Weight：518.41
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 73151-29-8 |
| Name | Fenticonazole Nitrate |
| Molecular Formula | C24H21Cl2N3O4S |
| Molecular Weight | 518.41 |
| Solubility | Soluble in DMSO ≥5mg/mL |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 277-302-6 |
| MDL | MFCD00941391 |
| SMILES | C1=CC=C(C=C1)SC2=CC=C(C=C2)COC(CN3C=CN=C3)C4=C(C=C(C=C4)Cl)Cl.[N+](=O)(O)[O-] |
| InChIKey | FJNRUWDGCVDXLU-UHFFFAOYSA-N |
| InChI | InChI=1S/C24H20Cl2N2OS.HNO3/c25-19-8-11-22(23(26)14-19)24(15-28-13-12-27-17-28)29-16-18-6-9-21(10-7-18)30-20-4-2-1-3-5-20;2-1(3)4/h1-14，17，24H，15-16H2;(H，2，3，4) |
| PubChem CID | 51754 |
| Target Point | Fungal |
| Passage | Anti-infection |
| Background | It is an antifungal imidazole ring derivative that acts by blocking ergosterol integration and sequentially destroying the outer cytoplasmic membrane. Effective against Gram-positive bacteria, mycosis and vaginal candidiasis. |
| Biological Activity | Fenticonazole Nitrate 是一种抗真菌咪唑环衍生物。作用原理是阻碍麦角甾醇的整合，并依次破坏细胞质外膜。对革兰氏阳性菌、霉菌病和阴道念珠菌病有效。[1-2] |
| Data Literature Source | [1]. Albash R，et al. Ultra-deformable liposomes containing terpenes (terpesomes) loaded fenticonazole nitrate for treatment of vaginal candidiasis: Box-Behnken design optimization，comparative ex vivo and in vivo studies. Drug Deliv. 2020 Dec;27(1):1514-1523. [2]. Fernández-Alba J，et al. Fenticonazole nitrate for treatment of vulvovaginitis: efficacy，safety，and tolerability of 1-gram ovules，administered as ultra-short 2-day regimen. J Chemother. 2004 Apr;16(2):179-86. |
| Unit | Bottle |
| Specification | 10mg 50mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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