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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Metabolic Enzyme & Protease > MonomyristinCAS：589-68-4
Molecular Formula：C17H34O4
Molecular Weight：302.45
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 589-68-4 |
| Name | Monomyristin |
| Molecular Formula | C17H34O4 |
| Molecular Weight | 302.45 |
| Solubility | Soluble in DMSO(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 248-329-0 |
| MDL | MFCD00046760 |
| SMILES | CCCCCCCCCCCCCC(=O)OCC(CO)O |
| InChIKey | DCBSHORRWZKAKO-UHFFFAOYSA-N |
| InChI | InChI=1S/C17H34O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-17(20)21-15-16(19)14-18/h16，18-19H，2-15H2，1H3 |
| PubChem CID | 79050 |
| Target Point | FAAH;Bacterial;Fungal |
| Passage | Metabolic Enzyme&Protease;Anti-infection |
| Background | Monomyristin inhibited the hydrolysis of 2-oleacylglycerol and the activity of fatty acid amide hydrolase, and had antibacterial and antifungal activities. |
| Biological Activity | Monomyristin 提取自 Serenoa repens，可抑制 2-oleoylglycerol 的水解（IC50=32 μM）和脂肪酸酰胺水解酶（FAAH）的活性（IC50=18 μM）。1-Monomyristin 对金黄色葡萄球菌（Staphylococcus aureus）和放线菌（Aggregatibacter actinomycetemcomitans）具有抗菌活性，对白色念珠菌（Candida albicans）也具有抗真菌活性。[1-3] |
| IC50 | FAAH: 18μM(IC50)[2] |
| Data Literature Source | [1]. Shimada H，et al. Biologically active acylglycerides from the berries of saw-palmetto (Serenoa repens). J Nat Prod. 1997 Apr;60(4):417-8. [2]. Vandevoorde S，et al. Influence of the degree of unsaturation of the acyl side chain upon the interaction of analogues of 1-arachidonoylglycerol with monoacylglycerol lipase and fatty acid amide hydrolase. Biochem Biophys Res Commun. 2005 Nov 11;337(1):104-9. [3]. Nurmala A，et al. Monomyristin and Monopalmitin Derivatives: Synthesis and Evaluation as Potential Antibacterial and Antifungal Agents. Molecules. 2018 Nov 29;23(12):3141. |
| Unit | Bottle |
| Specification | 10mg 25mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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