{{cart_num}}
My CartCAS：7177-50-6
Molecular Formula：C21H23N2NaO6S
Molecular Weight：454.47
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：Solid
Qty：
Size：
| CAS | 7177-50-6 |
| Name | Nafcillin Sodium |
| Molecular Formula | C21H23N2NaO6S |
| Molecular Weight | 454.47 |
| Solubility | Soluble in Water/DMSO(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD01941128 |
| SMILES | CCOC1=C(C2=CC=CC=C2C=C1)C(=O)NC3C4N(C3=O)C(C(S4)(C)C)C(=O)[O-].O.[Na+] |
| InChIKey | OCXSDHJRMYFTMA-KMFBOIRUSA-M |
| InChI | InChI=1S/C21H22N2O5S.Na.H2O/c1-4-28-13-10-9-11-7-5-6-8-12(11)14(13)17(24)22-15-18(25)23-16(20(26)27)21(2，3)29-19(15)23;;/h5-10，15-16，19H，4H2，1-3H3，(H，22，24)(H，26，27);;1H2/q;+1;/p-1/t15-，16+，19-;;/m1../s1 |
| PubChem CID | 23704143 |
| Target Point | β-lactamase |
| Passage | Anti-infection |
| Background | It is an antibiotic and a reversible β-lactamase inhibitor. It can be used in the study of staphylococcal infection. |
| Biological Activity | Nafcillin Sodium 是一种抗生素，是β-内酰胺酶的可逆抑制剂，Kd为33 mM，可用于葡萄球菌感染的研究。[1-3] |
| Data Literature Source | [1]. Tan AK，et al. Identification of the site of covalent attachment of nafcillin，a reversible suicide inhibitor of beta-lactamase. Biochem J. 1992 Jan 1;281 ( Pt 1)(Pt 1):191-6. [2]. SCHWICHTENBERG AH. A NEW SEMISYNTHETIC PENICILLIN: SODIUM NAFCILLIN. JAMA. 1965 Mar 15;191:930-1. [3]. Mortin LI，et al. Rapid bactericidal activity of daptomycin against methicillin-resistant and methicillin-susceptible Staphylococcus aureus peritonitis in mice as measured with bioluminescent bacteria. Antimicrob Agents Chemother. 2007 May;51(5):1787-94. |
| Unit | Bottle |
| Specification | 500mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Sorry, there is no more information.
Sorry, there is no more information.
Manual Download
